A nation so down on its team leading into the World Cup had swiftly been swept up in a wave of optimism following a start to their Group A campaign that even president Vladimir Putin wouldn't have dared dream.
Matters were made worse for Russian Federation in the 36th minute, Smolnikov picking up his second booking after lunging in on Cavani, just eight minutes after being carded for a foul on Matias Vecino.
Uruguay have won three consecutive World Cup matches against European opposition for the first time since a run of four straight victories between 1950 and 1954.
However, the hosts' plight took a further turn for the worse with 23 minutes played when, after Lucas Torreira's corner had been only half-cleared, Laxalt's fierce driver took a wicked deflection off Cheryshev and flew past the keeper to make it 2-0.
In the day's dead rubber Saudi Arabia got their first win of the tournament with a 2 - 1 over Egypt. "We have good players too, some are better than theirs", the coach said.
In-form Cheryshev had the chance to draw Russian Federation level nearly immediately but his half-volley from Artem Dzyuba's knockdown was too close to Galatasaray shot-stopper Fernando Muslera, who won his 100th global cap.
Luis Suarez grabbed his second goal of the tournament to open Uruguay's account with a free kick after 10 minutes and they doubled the lead with an own goal from Russia'sDenis Cheryshev soon afterwards.
90' GOAL!Uruguay 3-0 Russia: There's the goal Cavani has been desperate for all afternoon!
Cavani could have added a third just after the hour, but the Paris Saint-Germain striker elected to go down under pressure from Sergei Ignashevich rather than get a shot off, failing to fool referee Malang Diedhiou.
VOLGOGRAD, Russia - The oldest person to play in a World Cup match gave up a pair of goals, allowing Saudi Arabia to beat Egypt in a match between two teams that had already been eliminated.
SARANSK, Russia - Cristiano Ronaldo's missed penalty cost Portugal first place in its World Cup group.
But Suarez, Godin and Uruguay exposed their limitations in stark fashion here, ahead of a likely second-round meeting with Portugal or Spain.
The same goes for Russian Federation, who will face the Group B winners.
Uruguay are the first side to win all three of their group games without conceding a single goal since Argentina in 1998 (seven goals scored, none conceded).
She got into an argument with Austin , and the final moments of that squabble have now reverberated around the world. A woman threatened to call police on an 8-year-old girl selling water outside her apartment building.
McConnell already said in May that a potential Supreme Court battle would move to the front of the judicial confirmation pipeline. Mr Kennedy penned the Supreme Court's first major gay-rights decision in 1996, protecting LGBT Americans from discrimination.
Ardern has had little sleep over the past few days, with the baby also described as being "very alert and one hungry baby". It's the couple's first child together, and comes eight months after the 37 year old was sworn in as Prime Minister.
At the event, Trump also bashed "the mayor of San Diego" for warning citizens about immigration agent raids. But after public outcry, President Donald Trump on Wednesday ordered that they be brought back together.
Since Trump's executive order , Democrats have argued his search for a way out of one humanitarian crisis merely created another. She says this leaves groups like hers "uncertain" about how to manage those kids already in detention in the U.S.
Uber's policy is to ban any use of mobile devices by the safety driver while its autonomous vehicles are on public roads. The Arizona Republic reported that the driver was watching The Voice , a television musical talent show.
The dad looks pissed , and people can be heard remarking "no no no", "sir, he is scared" and "that's not allowed". In the video, the priest can be seen making a shape of the cross over the baby's body before he begins to cry.
Despite Mr Trump's stance, House Majority Leader Kevin McCarthy said the chamber would press ahead on legislation next week. The bill - which failed on a 193-231 vote - would not have provided DACA recipients a path to citizenship.
Five-goal Belgium say stand by for more
No need for Hazard to repeat his rebuke of Lukaku at half-time in the opener against Panama . Another against England would see them suspended for the first of the knockout games.
Utah’s Rudy Gobert wins NBA Defensive Player of the Year
Backstage, Robertson commended the activism of today's players, although he wondered why more white athletes aren't speaking out. Robertson is the career leader in triple-doubles and was the first player to average one for a season.
English bulldog wins title of World's Ugliest Dog
Here's what our winning pup's profile had to say about her life before World's Ugliest Dog stardom. A nine-year-old English bulldog called Zsa Zsa has won this year's world's ugliest dog contest.
Falcao scores, Colombia beats Poland 3-0 at World Cup
Colombia's win resurrects their World Cup campaign after defeat in their opener against Japan threatened an early exit. Colombia led 1-0 at half-time thanks to Yerry Mina's towering header following a well-worked short corner.
Marin Cilic beats Novak Djokovic to claim Queen's Club title
The Croat fought back to win the Fever-Tree Championships 5-7 7-6 (7-4) 6-3 in the longest final in the tournament's history. But with a 0-10 deficit against Djokovic, including twice in straight sets at Wimbledon , the odds are not in his favour.