The strikes, which fell close to the city's main public hospital, al-Thawra, hit the strategic city's fishing port and fish market.
The last attempt at peace talks for Yemen broke down in 2016.
Griffiths has been leading efforts to prevent a full-scale coalition assault on the strategic port city of Hodeidah on the Red Sea, which is responsible for more than 70 percent of imports to Yemen and is a vital lifeline for a country already teetering on the brink of starvation.
Reportssaid the drone has bombed the airport, but did not reveal any further details on damage to the airport or any possible casualties.
However, on 26 March 2015, a coalition of countries led by Saudi Arabia intervened militarily at the request of President Abd Rabbuh Mansour Hadi to secure the return of the Government to Sana'a, which had been seized by Houthi militias and allied units of the armed forces.
The Saudi-led coalition denied responsibility for the attack, saying it did not carry out any operations in the area that day.
Rebel-run Al Masirah TV reported that airstrikes left 52 people dead and more than 100 wounded.
About 70 percent of Yemen's food imports flow through Hodeidah port; about 8.4 million Yemenis are said by aid workers to be on the verge of starvation.
The Center also called for "full compliance with the provisions of worldwide humanitarian law", saying Houthis were in violation of this following the attack which killed dozens of civilians.
Earlier, Lise Grande, the United Nations humanitarian coordinator for Yemen, condemned the hospital attack as "shocking". "Nothing can justify this loss of life", she added.
However, Saudi Arabia claimed that Houthi fighters had attacked two oil tankers in the Red Sea, and thus it had chose to halt oil shipments via Bab el-Mandeb until the waterway was safe. In Hodeidah, one of the Yemeni army's largest offensives against the Houthi rebels is underway.
The UN special envoy for Yemen, Martin Griffiths, had urged the council to do more to "keep the Red Sea out of the conflict" as he unveiled plans to begin a first round of peace negotiations in Geneva on September 6.
He called for "an immediate ceasefire" and urged Yemen's warring parties to join United Nations peace efforts.
On Friday, the UN's World Health Organisation said Yemen may be on the brink of a new cholera epidemic, with greater chance of a high death rate due to widespread malnutrition.
Yemen's internationally recognised government is ready to attend UN-brokered talks next month in Geneva but is "not optimistic", a government official said on Friday.
Earlier, India dismissed England for 180 in their second innings, with fast bowler Ishant Sharma taking five for 51 in 13 overs. Following scans on Thursday, England have confirmed Jos Buttler did not suffer a fractured finger in the morning session.
On Thursday, her family and Crime Stoppers of Central Iowa held a news conference to announce the fund has so far raised $172,000. Yesterday, the reward for information leading to Tibbetts' safe return increased to $30,000.
A federal judge had ordered the reunions to be completed by Thursday but hundreds of children remain separated. Trump then claimed the United States has the "dumbest" and "worst" immigration laws in the world.
Anderson improved his length and troubled Kohli for the next two overs, before Rashid brought things to a close in this session. That was when Sam Curren was thrown the ball and in the spate of eight deliveries the left-arm pace ace got three wickets.
The Italian said that was one of the reasons his team were soundly beaten 2-0 by Manchester City in the Community Shield . I played against City last season, played them in their best moment of the season.
President Trump plans to impose 25 percent tariffs on $200 billion worth of imported Chinese goods, a report said on Tuesday . A first round of tariffs came into effect on 6 July, when the USA imposed 25% taxes on $34bn of Chinese imports.
Satellite photos reportedly show that North Korea continues work on developing intercontinental missile technology. Last Tuesday, Trump said new images signaled that North Korea was beginning to dismantle "a key missile site".
In August and November Iran faces two new waves of sanctions that will shut off their access to U.S. banking and oil exports. Last month, the U.S. rejected an European Union appeal to allow exemptions to the sanctions regime.
His main message focused on the devastation from wildfires seen across California that will only get "worse in the coming years". Redding Police on Tuesday asked for help from the public locating four people who are still missing.
The commission said it would delay releasing any results of the presidential race until all the votes are collated. The ZEC boss once again applauded the high vote turnout in the country's first post-Robert Mugabe elections.
Aussies eye PGA bounce-back after WGC slide
The world No.3 has 2014 WGC-Bridgestone victor Rory McIlroy (67) and Ian Poulter (70) snapping at his heels three shots back. His grandparents, Paul and Phyllis Thomas, watched him win for the first time on the PGA Tour.
Trump attacks LeBron James and Don Lemon over CNN interview
Yahoo News White House correspondent Hunter Walker points out that before James started criticizing Trump, Trump used to be a fan. He sits down with @donlemon at the opening of his new elementary school for at-risk children in his hometown of Akron, Ohio .
Presumed Korean War dead arrive in Hawaii
Indeed, the commitments regarding its nuclear weapons program were so vague as to be nearly meaningless, in my view. Australia, Belgium, France and the Philippines have yet to recover some of their war dead from North Korea.
Royal Family ‘FURIOUS at Meghan’s dad’ for Princess Diana rant
Sorry, Meghan: this is one filthy, sexy mush you won't be allowed to participate in, now that you're a part of the Royal Family . She told her biographer Andrew Morton that after her engagement to the Prince of Wales: "I cried like a baby to the four walls".
This Weekend's Tax Holiday is for More Than School Supplies
The state allows a wide variety of clothing items to go untaxed including fur coats, golf clothes, lingerie, and wedding apparel. Governor Scott Walker announced Wisconsin's first ever sales tax holiday that will start August 1st and run through August 5th.
Trump Receives Letter from North Korea's Kim
About 7,700 US soldiers are listed as missing from the conflict, and 5,300 of the remains are believed to still be in North Korea. Experts say that the painstaking identification process could take anywhere between days to decades to complete.